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СУЛЬФОРАФАН ПРИГНІЧУЄ ГЕПАТОЦЕЛЮЛЯРНУ КАРЦИНОМУ У МИШЕЙ ШЛЯХОМ АКТИВАЦІЇ P53, ЗМЕНШЕННЯ ОКСИДАТИВНОГО СТРЕСУ ТА ІНГІБУВАННЯ АНГІОГЕНЕЗУ

Background. Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Sulforaphane (SF) is a natural isothiocyanate that exhibits anticarcinogenic activity against various cancer cells in vivo and in vitro, with no observed side effects. It also has a prophylactic effect against ea...

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Bibliographic Details
Published in:Експериментальна онкологія
Date:2026
Volume:48
Issue:2
Pages:120-132
ISSN:2312-8852
Author Affiliations:
  • Kholoud A. Omran — Department of Zoology, Faculty of Science, Ain Shams University, Cairo, Egypt
  • Yomna I. Mahmoud — Department of Zoology, Faculty of Science, Ain Shams University, Cairo, Egypt
  • Asmaa A. Mahmoud — Department of Zoology, Faculty of Science, Ain Shams University, Cairo, Egypt
  • Nagui H. Fares — Department of Zoology, Faculty of Science, Ain Shams University, Cairo, Egypt
Main Authors: A. Omran, Kholoud, I. Mahmoud, Yomna, A. Mahmoud, Asmaa, H. Fares, Nagui
Format: Article
Language:English
Published: PH Akademperiodyka 2026
Subjects:
гепатоцелюлярна карцинома
сульфорафан
Bax
Bcl-2
VEGF
PCNA
p53
оксидативний стрес
миші
Online Access:https://exp-oncology.com.ua/index.php/Exp/article/view/644
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Journal Title:Experimental Oncology
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Experimental Oncology

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