Нанофiзика та антивiрусна терапiя

A new mechanism of interaction between viruses and nanoparticles is proposed. The mechanism is based on the local-field enhancement effect inherent only in nano-objects and can manifest itself in nanoparticle–virus systems. The basic idea consists in vacuum fluctuations that are always present in an...

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Datum:2018
Hauptverfasser: Lysenko, V., Lozovski, V., Spivak, M.
Format: Artikel
Sprache:English
Ukrainian
Veröffentlicht: Publishing house "Academperiodika" 2018
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Online Zugang:https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2018271
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Назва журналу:Ukrainian Journal of Physics

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Ukrainian Journal of Physics
id ujp2-article-2018271
record_format ojs
spelling ujp2-article-20182712019-02-27T09:16:25Z Nanophysics and Antiviral Therapy Нанофiзика та антивiрусна терапiя Lysenko, V. Lozovski, V. Spivak, M. плазмон-поляритон система наночастинка–вiрус plasmon-polariton nanoparticle–virus systems A new mechanism of interaction between viruses and nanoparticles is proposed. The mechanism is based on the local-field enhancement effect inherent only in nano-objects and can manifest itself in nanoparticle–virus systems. The basic idea consists in vacuum fluctuations that are always present in any physical system. This mechanism is universal and does not depend on the details of nanoparticle and virus structures, which was confirmed by numerous experiments carried out by us and in other scientific groups. A new method of purification of biofluids from nano-objects such as nanoparticles and viruses is also discussed. The method is based on a selective interaction between nano-objects and either a nanostructured surface, along which a surface plasmon-polariton propagates, or a system of nanothreads, on which a local plasmon-polariton is excited. On the basis of the method proposed for weakening the virus activity due to the action of a suspension of nanoparticles, a new effective way for the production of human leukocytic interferon has been developed and verified experimentally. Запропоновано новий механiзм взаємодiї вiрусiв з наночастинками, що ґрунтується на притаманному тiльки нанооб’єктам ефектi пiдсилення локального поля, який може проявлятись у системi наночастинка–вiрус. Основною iдеєю запропонованого механiзму є розгляд дiї завжди притаманного будь-якiй фiзичнiй системi поля вакуумних флуктуацiй. Цей механiзм є унiверсальним. Вiн не залежить вiд деталей структури наночастинки та вiрусу, що пiдтверджують численнi експерименти, проведенi як авторами роботи, так i iншими науковими групами. Обговорено також новий метод очищення бiорiдин вiд нанооб’єктiв – наночастинок та вiрусiв. Метод ґрунтується на вибiрковiй взаємодiї нанооб’єктiв з наноструктурованою поверхнею, вздовж якої поширюється поверхневий плазмон-поляритон, або з системою нанониток, що знаходяться в умовах збудження на них локального плазмон-поляритона. На основi запропонованого методу послаблення вiрусної активностi пiд дiєю суспензiї наночастинок, розроблено i експериментально перевiрено новий ефективний спосiб отримання людського лейкоцитарного iнтерферону. Publishing house "Academperiodika" 2018-10-05 Article Article Peer-reviewed Рецензована стаття application/pdf application/pdf https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2018271 10.15407/ujpe58.01.0077 Ukrainian Journal of Physics; Vol. 58 No. 1 (2013); 77 Український фізичний журнал; Том 58 № 1 (2013); 77 2071-0194 2071-0186 10.15407/ujpe58.01 en uk https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2018271/191 https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2018271/192 Copyright (c) 2018 Bogolyubov Institute for Theoretical Physics, National Academy of Sciences of Ukraine
institution Ukrainian Journal of Physics
baseUrl_str
datestamp_date 2019-02-27T09:16:25Z
collection OJS
language English
Ukrainian
topic плазмон-поляритон
система наночастинка–вiрус
spellingShingle плазмон-поляритон
система наночастинка–вiрус
Lysenko, V.
Lozovski, V.
Spivak, M.
Нанофiзика та антивiрусна терапiя
topic_facet плазмон-поляритон
система наночастинка–вiрус
plasmon-polariton
nanoparticle–virus systems
format Article
author Lysenko, V.
Lozovski, V.
Spivak, M.
author_facet Lysenko, V.
Lozovski, V.
Spivak, M.
author_sort Lysenko, V.
title Нанофiзика та антивiрусна терапiя
title_short Нанофiзика та антивiрусна терапiя
title_full Нанофiзика та антивiрусна терапiя
title_fullStr Нанофiзика та антивiрусна терапiя
title_full_unstemmed Нанофiзика та антивiрусна терапiя
title_sort нанофiзика та антивiрусна терапiя
title_alt Nanophysics and Antiviral Therapy
description A new mechanism of interaction between viruses and nanoparticles is proposed. The mechanism is based on the local-field enhancement effect inherent only in nano-objects and can manifest itself in nanoparticle–virus systems. The basic idea consists in vacuum fluctuations that are always present in any physical system. This mechanism is universal and does not depend on the details of nanoparticle and virus structures, which was confirmed by numerous experiments carried out by us and in other scientific groups. A new method of purification of biofluids from nano-objects such as nanoparticles and viruses is also discussed. The method is based on a selective interaction between nano-objects and either a nanostructured surface, along which a surface plasmon-polariton propagates, or a system of nanothreads, on which a local plasmon-polariton is excited. On the basis of the method proposed for weakening the virus activity due to the action of a suspension of nanoparticles, a new effective way for the production of human leukocytic interferon has been developed and verified experimentally.
publisher Publishing house "Academperiodika"
publishDate 2018
url https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2018271
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AT lozovskiv nanofizikataantivirusnaterapiâ
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