Энергетика димеризации лигандов, связывающихся в малый желобок ДНК

• Date: 2018
• Main Authors: Kostjukov, V. V., Miloserdova, Yu. G., Shram, O. A., Rubinson, M. A., Evstigneev, M. P.
• Format: Article
• Language: English; Ukrainian
• Published: Publishing house "Academperiodika" 2018
• Subjects: лекситропсины; димер; пептидная группа; ароматическое кольцо; энергетические вклады
• Online Access: https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2018471
• Journal Title: Ukrainian Journal of Physics

The energy analysis of a dimerization in aqueous solutions of seven biologically active lexitropsins, which are different by structure, was carried out with the use of the molecular simulation method. The main stabilization of dimers was shown to take place owing to hydrophobic and intermolecular va...