Особливості комплексоутворення в гетеросистемі “доксорубіцин–бичачий сироватковий альбумін–наночастинки золота”. Дослідження флуоресценції

The fluorescence (FL) quenching in aqueous solutions of doxorubicin (DOX)–bovine serum albumin (BSA)–gold nanoparticles (AuNPs) is studied. The existence of additional mechanisms of DOX-BSA complex formation leading to an increase in the binding constant K and a decrease in the number of binding sit...

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Datum:2020
Hauptverfasser: Goncharenko, N. A., Dmytrenko, O. P., Pavlenko, O. L., Kulish, M. P., Pundyk, I. P., Lesyuk, A. I., Busko, T. O., Lopatynskyy, A. M., Chegel, V. I., Lytvyn, V. K., Kaniuk, M. I.
Format: Artikel
Sprache:English
Veröffentlicht: Publishing house "Academperiodika" 2020
Schlagworte:
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Online Zugang:https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2019520
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Назва журналу:Ukrainian Journal of Physics

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Ukrainian Journal of Physics
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Zusammenfassung:The fluorescence (FL) quenching in aqueous solutions of doxorubicin (DOX)–bovine serum albumin (BSA)–gold nanoparticles (AuNPs) is studied. The existence of additional mechanisms of DOX-BSA complex formation leading to an increase in the binding constant K and a decrease in the number of binding sites n and the distance between the fluorophore and energy acceptors due to the presence of gold nanoparticles is shown.