Особливості деформацій, які виникають у клітині при проникненні в неї коронавірусу

A mathematical model has been proposed to describe the deformation behavior of a cell, when a coronavirus enters it. The model is continuum-based, and the theory of elasticity is used in calculations. It was found that the deformation process accompanying the penetration of coronavirus consists of t...

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Datum:2021
Hauptverfasser: Bulavin, L.A., Zabashta, Yu.F., Hnatiuk, K.I.
Format: Artikel
Sprache:English
Ukrainian
Veröffentlicht: Publishing house "Academperiodika" 2021
Schlagworte:
Online Zugang:https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2021015
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Назва журналу:Ukrainian Journal of Physics

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Ukrainian Journal of Physics
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Zusammenfassung:A mathematical model has been proposed to describe the deformation behavior of a cell, when a coronavirus enters it. The model is continuum-based, and the theory of elasticity is used in calculations. It was found that the deformation process accompanying the penetration of coronavirus consists of two stages. At the first stage, the deformations of cytoplasmic membrane are elastic. At the second stage, the structure of a cytoplasmic membrane is destroyed. The dependence of the energy of the “coronavirus–cell” system on the size of the contact zone that separates the coronavirus and the cell was obtained. The existence of an energy barrier that separates both stages of the deformation process was proved. As a result, the penetration of the coronavirus terminates at the end of the first stage. However, the energy barrier can be overcome due to thermal fluctuations.