A note on global attractivity in models of hematopoiesis

We consider the delay differential equations \(P'(t) = \frac{{\beta _0 \theta ^n [P(t - \tau )]^j }}{{\theta ^n + [P(t - \tau )]^n }} - \delta P(t),{\rm{ }}j = 0,1,\) which were proposed by Mackey and Glass as a model of blood cell production. We suggest new conditions sufficient for th...

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Bibliographic Details
Date:1998
Main Authors: Gopalsamy, К., Гопалсамі, К.
Format: Article
Language:English
Published: Institute of Mathematics, NAS of Ukraine 1998
Online Access:https://umj.imath.kiev.ua/index.php/umj/article/view/4967
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Journal Title:Ukrains’kyi Matematychnyi Zhurnal
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Ukrains’kyi Matematychnyi Zhurnal
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Summary:We consider the delay differential equations \(P'(t) = \frac{{\beta _0 \theta ^n [P(t - \tau )]^j }}{{\theta ^n + [P(t - \tau )]^n }} - \delta P(t),{\rm{ }}j = 0,1,\) which were proposed by Mackey and Glass as a model of blood cell production. We suggest new conditions sufficient for the positive equilibrium of the equation considered to be a global attractor. In contrast to the Lasota-Wazewska model, we establish the existence of the number δj = δj(n, τ) > 0 such that the equilibrium of the equation under consideration is a global attractor for all δ ε (0, δj] independently of β0 and θ.