Photolon enhanccement of ultrasound cytotoxicity

Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the con...

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Видавець:Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
Дата:2011
Автори: Tserkovsky, D.A., Alexandrova, E.N., Istomin, Yu.P.
Формат: Стаття
Мова:English
Опубліковано: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2011
Назва видання:Experimental Oncology
Теми:
Онлайн доступ:http://dspace.nbuv.gov.ua/handle/123456789/138614
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Цитувати:Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
id irk-123456789-138614
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spelling irk-123456789-1386142018-06-20T03:08:20Z Photolon enhanccement of ultrasound cytotoxicity Tserkovsky, D.A. Alexandrova, E.N. Istomin, Yu.P. Short communications Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the concentration of 1 µg/ml in the culture medium, and then cell viability was evaluated. Results: Photolon increased the cytotoxic effect of ultrasound by 1.5-2.3-fold but had no effect on its cytostatic activity. Conclusion: Photolon produces a pronounced sonosensitizing effect on glioma C6 cells and is a promising drug for sonodynamic treatment of malignant tumors. 2011 Article Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/138614 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
language English
topic Short communications
Short communications
spellingShingle Short communications
Short communications
Tserkovsky, D.A.
Alexandrova, E.N.
Istomin, Yu.P.
Photolon enhanccement of ultrasound cytotoxicity
Experimental Oncology
description Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the concentration of 1 µg/ml in the culture medium, and then cell viability was evaluated. Results: Photolon increased the cytotoxic effect of ultrasound by 1.5-2.3-fold but had no effect on its cytostatic activity. Conclusion: Photolon produces a pronounced sonosensitizing effect on glioma C6 cells and is a promising drug for sonodynamic treatment of malignant tumors.
format Article
author Tserkovsky, D.A.
Alexandrova, E.N.
Istomin, Yu.P.
author_facet Tserkovsky, D.A.
Alexandrova, E.N.
Istomin, Yu.P.
author_sort Tserkovsky, D.A.
title Photolon enhanccement of ultrasound cytotoxicity
title_short Photolon enhanccement of ultrasound cytotoxicity
title_full Photolon enhanccement of ultrasound cytotoxicity
title_fullStr Photolon enhanccement of ultrasound cytotoxicity
title_full_unstemmed Photolon enhanccement of ultrasound cytotoxicity
title_sort photolon enhanccement of ultrasound cytotoxicity
publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
publishDate 2011
topic_facet Short communications
url http://dspace.nbuv.gov.ua/handle/123456789/138614
citation_txt Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ.
series Experimental Oncology
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AT alexandrovaen photolonenhanccementofultrasoundcytotoxicity
AT istominyup photolonenhanccementofultrasoundcytotoxicity
first_indexed 2023-10-18T21:18:47Z
last_indexed 2023-10-18T21:18:47Z
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