Photolon enhanccement of ultrasound cytotoxicity
Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the con...
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| Дата: | 2011 |
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| Автори: | , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2011
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| Назва видання: | Experimental Oncology |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/138614 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| id |
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irk-123456789-1386142018-06-20T03:08:20Z Photolon enhanccement of ultrasound cytotoxicity Tserkovsky, D.A. Alexandrova, E.N. Istomin, Yu.P. Short communications Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the concentration of 1 µg/ml in the culture medium, and then cell viability was evaluated. Results: Photolon increased the cytotoxic effect of ultrasound by 1.5-2.3-fold but had no effect on its cytostatic activity. Conclusion: Photolon produces a pronounced sonosensitizing effect on glioma C6 cells and is a promising drug for sonodynamic treatment of malignant tumors. 2011 Article Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/138614 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Short communications Short communications |
| spellingShingle |
Short communications Short communications Tserkovsky, D.A. Alexandrova, E.N. Istomin, Yu.P. Photolon enhanccement of ultrasound cytotoxicity Experimental Oncology |
| description |
Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the concentration of 1 µg/ml in the culture medium, and then cell viability was evaluated. Results: Photolon increased the cytotoxic effect of ultrasound by 1.5-2.3-fold but had no effect on its cytostatic activity. Conclusion: Photolon produces a pronounced sonosensitizing effect on glioma C6 cells and is a promising drug for sonodynamic treatment of malignant tumors. |
| format |
Article |
| author |
Tserkovsky, D.A. Alexandrova, E.N. Istomin, Yu.P. |
| author_facet |
Tserkovsky, D.A. Alexandrova, E.N. Istomin, Yu.P. |
| author_sort |
Tserkovsky, D.A. |
| title |
Photolon enhanccement of ultrasound cytotoxicity |
| title_short |
Photolon enhanccement of ultrasound cytotoxicity |
| title_full |
Photolon enhanccement of ultrasound cytotoxicity |
| title_fullStr |
Photolon enhanccement of ultrasound cytotoxicity |
| title_full_unstemmed |
Photolon enhanccement of ultrasound cytotoxicity |
| title_sort |
photolon enhanccement of ultrasound cytotoxicity |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2011 |
| topic_facet |
Short communications |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/138614 |
| citation_txt |
Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ. |
| series |
Experimental Oncology |
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2023-10-18T21:18:47Z |
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2023-10-18T21:18:47Z |
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