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Cloning of variable fragments of tumor immunoglobulin, assembling and expressing of human SCFV protein in E. coli for anti-idiotype vaccination

Aim: Idiotype, the unique part of immunoglobulin molecule expressed on the surface of B-cells, represents a specific antigen for vaccination against lymphoma. We have developed a rapid method for immunoglobulin variable fragments cloning, assembling and expression of recombinant idiotype protein in...

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Bibliographic Details
Main Authors: Meleshko, A.N., Vashkevich, K.P., Fomina, E.G., Scheslenok, E.P., Schkolina, T.V., Sergeev, G.V.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2013
Series:Experimental Oncology
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Online Access:http://dspace.nbuv.gov.ua/handle/123456789/139103
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