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Epothilone B induces glioblastoma cell death via survivin down-regulation

The clinical resistance of glioblastomas to chemotherapeutic agents can be attributed to drug efflux pumps, such as P-glycoprotein, which contributes to reduce drug efficacy. The present study examined the utility of epothilone B, which is not a substrate for P-glycoprotein, on glioblastoma cells. M...

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Bibliographic Details
Main Author: Quick, Q.A.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2008
Series:Experimental Oncology
Subjects:
Online Access:http://dspace.nbuv.gov.ua/handle/123456789/139919
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