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Enhanced cytotoxicity of рhotoexcited fullerene C60 and cisplatin combination against drug-resistant leukemic cells

Enhanced cytotoxicity of рhotoexcited fullerene C60 and cisplatin combination against drug-resistant leukemic cells

Aim: To evaluate the viability of leukemic cells sensitive (L1210S) and resistant (L1210R) to cisplatin, ROS production and free cytosolic Ca²⁺ concentration under treatment with cisplatin or its combination with photoexcited fullerene C₆₀. Methods: Cell viability was assessed by the MTT reduction a...

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Bibliographic Details
Main Authors: Franskevych, D.V., Prylutska, S.V., Grynyuk, I.I., Grebinyk, D.M., Matyshevska, O.P.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2015
Series:Experimental Oncology
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Online Access:http://dspace.nbuv.gov.ua/handle/123456789/145486
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http://dspace.nbuv.gov.ua/handle/123456789/145486

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