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Analysis of the 3′UTR region of the NOTCH1 gene in chronic lymphocytic leukemia patients

Analysis of the 3′UTR region of the NOTCH1 gene in chronic lymphocytic leukemia patients

Deregulation of NOTCH1-signalling pathway is common in chronic lymphocytic leukemia (CLL). The most of studies are focused on detection of the hotspot c.7541_7542delCT NOTCH1 mutations in exon 34, while studies of mutations in the 3′UTR region are rare. The aims of work were to evaluate the frequenc...

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Bibliographic Details
Main Authors: Abramenko, I.V., Bilous, N.I., Chumak, A.A., Dyagil, I.S., Martina, Z.V.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2018
Series:Experimental Oncology
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Online Access:http://dspace.nbuv.gov.ua/handle/123456789/145636
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http://dspace.nbuv.gov.ua/handle/123456789/145636

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