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Mitochondria do not play a major role in landomycin E-induced ROS burst and circumvention of multiple drug resistance in HL-60 leukemia cells

Mitochondria do not play a major role in landomycin E-induced ROS burst and circumvention of multiple drug resistance in HL-60 leukemia cells

Aim. To study the molecular mechanisms of reactive oxygen species (ROS) involvement in circumventing the cancer drug resistance by novel angucycline antibiotic landomycin E in HL-60 human leukemia cells and its drug-resistant sublines HL-60/adr and HL-60/vinc. Methods. MTT assay, trypan blue exclusi...

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Bibliographic Details
Main Authors: Panchuk, R.R., Lehka, L.V., Rohr, J., Berger, W., Stoika, R.S.
Format: Article
Language:English
Published: Інститут молекулярної біології і генетики НАН України 2016
Series:Вiopolymers and Cell
Subjects:
Genomics, Transcriptomics and Proteomics
Online Access:http://dspace.nbuv.gov.ua/handle/123456789/152824
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http://dspace.nbuv.gov.ua/handle/123456789/152824

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