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Implementation of the quantitative Real-Time PCR for the molecular-genetic diagnostics of spinal muscular atrophy
Aim. To develop an easy and reliable assay for quantitative analysis of the SMN1 gene exon 7 copy number with Real-Time PCR and a SYBR Green dye which can be used as a test-system for spinal muscular atrophy (SMA) diagnostics. Methods. For the quantification the SMN1 gene exon 7 copies we have used...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Інститут молекулярної біології і генетики НАН України
2010
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Series: | Вiopolymers and Cell |
Subjects: | |
Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/153859 |
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