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Interaction of cyanine dyes with nucleic acids. 4. Efficient 5-fluorescent labelling of oligonucleotides with monomethyne pyrylium cyanine dye, Cyan 39

A new system for fluorescent 5'-end labelling of oligonucleotides with cyanine dyes is proposed. Reaction of primary amine with pyrylium salt was used for the efficient conjugation of monomethyne pyrylium cyanine dye with 5'-aminoalkyl oligonucleotide with simultaneous conversion of the «b...

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Bibliographic Details
Main Authors: Yarmoluk, S.M., Kostenko, A.M., Kornushyna, O.S., Dubey, I.Y.
Format: Article
Language:English
Published: Інститут молекулярної біології і генетики НАН України 1998
Series:Биополимеры и клетка
Subjects:
Online Access:http://dspace.nbuv.gov.ua/handle/123456789/154137
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