Optimization of nucleosome assembly from histones and model DNAs and estimation of the reconstitution efficiency

• Дата: 2019
• Автори: Kutuzov, M.M., Kurgina, T.A., Belousova, E.A., Khodyreva, S.N., Lavrik, O.I.
• Формат: Стаття
• Мова: English
• Опубліковано: Інститут молекулярної біології і генетики НАН України 2019
• Назва видання: Вiopolymers and Cell
• Теми: Structure and Function of Biopolymers
• Онлайн доступ: http://dspace.nbuv.gov.ua/handle/123456789/154398
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Цитувати: Optimization of nucleosome assembly from histones and model DNAs and estimation of the reconstitution efficiency / M.M. Kutuzov, T.A. Kurgina, E.A. Belousova, S.N. Khodyreva, O.I. Lavrik // Вiopolymers and Cell. — 2019. — Т. 35, № 2. — С. 91-98. — Бібліогр.: 12 назв. — англ.

Nucleosome core particles (NCPs) are basic units of chromatin organization; they represent the most convenient model system for the study of key DNA-dependent processes. Therefore, a robust method of nucleosome assembly is important for research. To prepare NCPs, purified histones and DNAs with sequ...