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Synthesis of model DNA and their application as substrates of nucleotide excision repair

Synthesis of model DNA and their application as substrates of nucleotide excision repair

Aim. Nucleotide excision repair (NER) is DNA repair system responsible to remove bulky lesions from DNA. These lesions appear in DNA as consequence of UV-light irradiation or environmental stress. Study of NER is extremely important to improve action of chemotherapeutic drugs. Methods. In vitro NER-...

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Bibliographic Details
Main Authors: Evdokimov, A.N., Tsidulko, A.Yu., Petruseva, I.O., Koroleva, L.S., Serpokrylova, I.Yu., Silnikov, V.N., Lavrik, O.I.
Format: Article
Language:English
Published: Інститут молекулярної біології і генетики НАН України 2012
Series:Вiopolymers and Cell
Subjects:
Structure and Function of Biopolymers
Online Access:http://dspace.nbuv.gov.ua/handle/123456789/156845
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http://dspace.nbuv.gov.ua/handle/123456789/156845

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