The level of blood plasma mitochondrial DNA upon acute myocardium damage in experiment

• Main Authors: Sudakov, N.P., Popkova, T.P., Novikova, M.A., Katyshev, A.I., Nikiforov, S.B., Pushkarev, B.G., Goldberg, O.A., Klimenkov, I.B., Lepekhova, S.A., Ezhikeeva, S.D., Ten, M.N., Osipov, V.G., Konstantinov, Yu.M.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2012
• Series: Вiopolymers and Cell
• Subjects: Short Communications
• Online Access: http://dspace.nbuv.gov.ua/handle/123456789/156936

The aim of the present investigation is to study the level of plasma mtDNA as a potential marker of cardiomyocyte damage in 2 and 4 h after subcutaneous injection of adrenaline and during the formed morphological alterations of the myocardium (3 days). Methods. Real time PCR. Male Wistar rats were u...