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Fluorescence intensity profiles of in situ hybridization signals depict genome architecture within human interphase nuclei

An approach towards construction of two-dimensional (2D) and three-dimensional (3D) profiles of interphase chromatin architecture by quantification of fluorescence in situ hybridization (FISH) signal intensity is proposed. The technique was applied for analysis of signal intensity and distribution w...

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Bibliographic Details
Main Authors: Iourov, I.Y., Vorsanova, S.G., Yurov, Y.B.
Format: Article
Language:English
Published: Інститут клітинної біології та генетичної інженерії НАН України 2008
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Online Access:http://dspace.nbuv.gov.ua/handle/123456789/8218
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