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Fluorescence intensity profiles of in situ hybridization signals depict genome architecture within human interphase nuclei
An approach towards construction of two-dimensional (2D) and three-dimensional (3D) profiles of interphase chromatin architecture by quantification of fluorescence in situ hybridization (FISH) signal intensity is proposed. The technique was applied for analysis of signal intensity and distribution w...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Інститут клітинної біології та генетичної інженерії НАН України
2008
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Subjects: | |
Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/8218 |
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