Influence of two pt(iv) complexes on viability, apoptosis and cell cycle of B16 mouse melanoma tumors

• Published in: Experimental Oncology
• Date: 2009
• Main Authors: Kaznica, A., Drewa, T., Lakomska, I., Ryta-Stamirowska, P., Debski, R., Styczynski, J., Drewa, G., Szłyk, E.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2009
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/135114
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Influence of two pt(iv) complexes on viability, apoptosis and cell cycle of B16 mouse melanoma tumors / A. Kaznica, T. Drewa, I. Lakomska, P. Ryta-Stamirowska, R. Debski, J. Styczynski, G. Drewa, E. Szłyk // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 33–36. — Бібліогр.: 19 назв. — англ.

Several platinum(IV) complexes are showing considerable promise in initial trials, producing reactive intermediates that then interact with DNA.
 Aim: To perform in vitro study of two new platinum(IV) complexes cytotoxic effect on B16 mouse melanoma cells. Methods: PtCl₄
 (dbtp)₂ a...