Combination of cyclooxygenase-2 inhibitor and doxorubicin increases the growth inhibition and apoptosis in human hepatocellular carcinoma cells

• Published in: Experimental Oncology
• Date: 2007
• Main Authors: Pan, Y.Y., Xu, S.P., Jia, X.Y., Xu, H.Q., Zhang, Y., Rui, L.X., Wei, W.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2007
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138556
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Combination of cyclooxygenase-2 inhibitor and doxorubicin increases the growth inhibition and apoptosis in human hepatocellular carcinoma cells / Y.Y. Pan, S.P. Xu, X.Y. Jia, H.Q. Xu, Y. Zhang, L.X. Rui, W. Wei // Experimental Oncology. — 2007. — Т. 29, № 1. — С. 23-29. — Бібліогр.: 45 назв. — англ.

Inhibition of cyclooxygenase (COX)-2 elicits therapeutic effects in solid tumors that are coupled with the inhibition of cell proliferation and induction of apoptosis in tumor cells. Aim: This study was designed to investigate the role of COX-2 inhibitor nimesulide in cell growth and apoptosis of th...