R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2010
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| Schriftenreihe: | Experimental Oncology |
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| Zitieren: | R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary // Experimental Oncology. — 2010. — Т. 32, № 3. — С. 118-119. — англ. |
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nasplib_isofts_kiev_ua-123456789-1386122025-02-09T13:49:41Z R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary Kavetsky, R.E. Preface 2010 Article R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary // Experimental Oncology. — 2010. — Т. 32, № 3. — С. 118-119. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/138612 en Experimental Oncology application/pdf Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
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Preface Preface |
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Preface Preface Kavetsky, R.E. R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary Experimental Oncology |
| format |
Article |
| author |
Kavetsky, R.E. |
| author_facet |
Kavetsky, R.E. |
| author_sort |
Kavetsky, R.E. |
| title |
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary |
| title_short |
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary |
| title_full |
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary |
| title_fullStr |
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary |
| title_full_unstemmed |
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary |
| title_sort |
r.e. kavetsky institute of experimental pathology, oncology and radiobiology, nas of ukraine — 50th anniversary |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2010 |
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Preface |
| url |
https://nasplib.isofts.kiev.ua/handle/123456789/138612 |
| citation_txt |
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine — 50th Anniversary // Experimental Oncology. — 2010. — Т. 32, № 3. — С. 118-119. — англ. |
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Experimental Oncology |
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2025-11-26T11:48:56Z |
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| fulltext |
118 Experimental Oncology 32, 118–119, 2010 (September)
R.E. Kavetsky Institute of Experimental Patho-
logy, Oncology and Radiobiology (IEPOR) of National
Academy of Sciences (NAS) of Ukraine was founded in
1960 by Council of Ministers of UkrSSR. The main aims
of the new Institute were to intensify the investigations
in the field of oncology, to allow the practical help for
clinics and hospitals and to train the physicians spe-
cializing in surgical, medical and radiological oncology.
The founder and the first director of the Institute was
a famous oncologist and pathophysiologist Academi-
cian R.E. Kavetsky. Fruitful work of the Institute allowed
improving significantly the level of oncological health
care in Ukraine, initiating a number of priority studies
in the field of experimental and clinical oncology that
resulted in the significant enlargement of scientific
research trends. This promoted the decision of the
Council of Ministers of UkrSSR to transfer the Institute
to the Academy of Sciences of UkrSSR in 1971 with the
new title — Institute of Oncology Problems of Academy
of Sciences of UkrSSR. The Institute has accounted
302 collaborators, including 102 scientific researchers,
12 Doctors of Sciences, and 64 Ph.D. After the death
of Academician R.E. Kavetsky in 1978, the Institute has
been headed by his disciple Academician V.G. Pinchuk,
and the Institute has been named by its founder R.E. Ka-
vetsky. Taking into account the broadened scientific
subjects in 1991 the Institute has been re-named as R.E.
Kavetsky Institute of Experimental Pathology, Oncology
and Radiobiology, Academy of Sciences of Ukraine. At
present time the Institute is headed by Academician of
NAS of Ukraine V.F. Chekhun.
Scientific activity of many prominent scientists of
Ukraine who have made a significant impact in the de-
velopment of important fundamental and applied prob-
lems of molecular oncology, experimental pathology,
immunology and radiobiology, has been closely related
to this Institute. Activity of R.E. Kavetsky, V.G. Pinchuk,
Z.A. Butenko, K.P. Ganina, D.G. Zatula, Yu.O. Umansky,
G.I. Kulik and many other scientists promoted quick
progress in studies in a number of scientific fields: «Cy-
tology of tumor growth»; «Research of molecular and
cellular mechanisms of leukaemogenesis»; «Genetics
of human cancer»; «Biotherapy. Natural anticancer
compounds»; «Immunology of malignant growth».
Due to the fruitful work of collaborators of the
Institute, there have been initiated and are presently
under development the priority research activities that
are recognized world-wide, namely «Radiobiological
and ecologic aspects of Chernobyl power plant ac-
cident», «Study of biological action of laser irradia-
tion and development of methods of photodynamic
therapy of neoplasia», «Cancer stem cells», «Study
of pathogenetic aspects of metastasis», «Molecular
basis and medico-biological problems of pharma-
cologic resistance», «Tumor cell microenvironment»,
«Fundamental mechanisms, means and methods of
sorption detoxification therapy».
Presently IEPOR NAS of Ukraine is a potent center
of scientific research devoted to the most actual prob-
lems of experimental pathology, molecular oncology,
radiobiology and biotechnology. In the Institute there
are 11 scientific departments where 284 collaborators
work, including 140 researchers, from which — 1 Aca-
demician of NASU, 25 Doctors of Sciences, 67 Ph.D.
and 17 post-graduate students.
Among the most important innovative develop-
ments of the Institute one could mention technology
of early and differential diagnostics of precancerous
and cancerous processes of different localizations;
methods for evaluation of tumor sensitivity to antican-
cer means preparations to prognose the therapeutic
efficacy and individualize the treatment; medico-
genetic consultation of oncological patients and their
family members; evaluation of genome instability of
peripheral blood lymphocytes; determination of hu-
man individual radiation sensitivity; molecular methods
of prognosis of disease outcome.
There has been developed an original anticancer
vaccine on the basis of patients’ tumor antigens and
adjuvants of bacterial origin that is used in clinics.
Significant progress has been made also in the
field of nanotechnology, in particular, for the first time
nanocomposites of ferrous oxide for creation of vector
system for delivery of anticancer preparations have
been produced.
The achievements of the scientists of the Institute
have been highly appraised by the Government of
Ukraine and by scientific community: 14 scientists
are the Laureates of State Awards, 20 scientists were
awarded by personal Award of NAS of Ukraine, 7 sci-
entists received degree of «Honored Worker of Science
and Technology of Ukraine». Scientific achievements
are reflected in more than 150 patents and more than
300 monographs that have been highly appreciated
by scientific community.
The Institute pays a great attention to coordination
of scientific research in the field of experimental and
clinical oncology, and cooperates with scientific and
educational organizations of Ukraine, regional and
city oncological hospitals for implementation of the
developments of fundamental oncology into medical
practice. On the basis of the Institute a Problem Com-
mission «Oncology» of Ministry of Health and Academy
of Medical Sciences of Ukraine is functioning.
PREFACE
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine —
50th Anniversary
Exp Oncol 2010
32, 3, 118–119
Experimental Oncology 32, 118–119, 2010 (September) 119
The Institute provides the cooperation with many
universities and oncological centers of Great Britain,
Spain, Italy, Canada, Germany, France, USA, Sweden,
Switzerland, Japan.
Since 1994 the Institute is the only one organization
from Ukraine which is the associated member of the
Organization of European Cancer Institutes (OECI-
EEIG). The leading scientists of IEPOR are associ-
ated members of international organizations: ASCO,
ВACR, EACR, ESMO, ESHO, INCTR, IFCC, SRA, etc.
The Institute is a founder of International scientific-
theoretical journal «Experimental Oncology» (1979)
and scientific-practical journal «Oncologiya» (1999),
that are widely recognized in Ukraine, CIS and many
countries in the world.
On the basis of IEPOR of NAS of Ukraine there has
been created and functions the Bank of cell and tissue
cultures of man and animals — a unique collection
of cell cultures and tumor strains for performance of ex-
perimental studies, which belongs to National Heritage
of Ukraine. The treasury of Institute library accounts
49244 scientific journals and 18687 monographs.
In accordance with the order of the President
of Ukraine an International Conference «Tumor and
Organism: New Aspects of Old Problem» will be held on
September 21–24th, 2010, in Kiev. This scientific meet-
ing is devoted to the 50th anniversary of the Institute.
It is planned to discuss up to date results of studies on
interaction between tumor and host, to appoint the pri-
ority directions in the creation of methods for preclinical
diagnostics and high-tech means of anticancer therapy.
The program of the Conference includes 5 sections:
the first section will focus on the basic aspects of tumor
biology and immunology. Topics include mechanisms
that determine metastasis and homing of tumor cells,
tumor angiogenesis, the biology and molecular biol-
ogy of cancer stem cells, immunological aspects of
tumor-host interaction. The second section will focus
on the tumor microenvironment as a key factor in tumor
development and progression. Topics include hypoxia
signaling, angiogenesis, aerobic glycolysis in human
tumors as a basis for diagnostics and anticancer stra-
tegies, inflammation and cancer. The third section will
cover fundamental and practical aspects of tumor mar-
kers: identification of novel tumor markers, peculiarity
of signal transduction pathways in tumor cells, applica-
tion of tumor markers and cell differentiation antigens
for cancer diagnosis and prognosis. The forth section
will focus of underlying mechanisms of carcinogen-
esis and cancer prevention. Special emphasis will be
given on the role of genetic and epigenetic alterations
and their interaction in cancer development and novel
approaches for creating of sensitive markers for early
detection of prevention of cancer. The fifth section will
cover the clinical and experimental investigation of can-
cer therapy mediated through tumor-host interaction
(biotherapy, vascular disruptive therapy, etc.), validation
of new targets for cancre therapy, and new strategies
for delivering therapy to tumors. The special attention
will be devoted to the problem of individualized therapy
of cancer patients.
The materials of plenary and session lectures
presented on conference are published in the current
issue of «Experimental Oncology». In the next issue the
publication of conference materials will be continued.
Editorial Board
of the journal «Experimental Oncology»
Copyright © Experimental Oncology, 2010
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