Progressive multifocal leukoencephalopathy following fludarabine treatment in a chronic lymphocytic leukemia patient

• Published in: Experimental Oncology
• Date: 2011
• Main Authors: Lejniece, S., Murovska, M., Chapenko, S., Breiksa, B., Jaunmuktane, Z., Feldmane, L., Ziedlina, I., Gomez-Roman, J., Garcia-Cabeza, M., Lejnieks, A.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2011
• Subjects: Short communications
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138666
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Progressive multifocal leukoencephalopathy following fludarabine treatment in a chronic lymphocytic leukemia patient / S. Lejniece, M. Murovska, S. Chapenko, B. Breiksa, Z. Jaunmuktane, L. Feldmane, I. Ziedlina, J. Gomez-Roman, M. Garcia-Cabeza, A. Lejnieks // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 239-241. — Бібліогр.: 13 назв. — англ.

Progressive multifocal leukoencephalopathy (PML) is a neurological disease caused by infection of the central nervous system (CNS) with the JC polyomavirus (JCV). JCV is endemic and infects a large proportion (70–90%) of healthy individuals worldwide, but infection is latent. JCV reactivation may oc...