Effect of combined treatment with insulin, metformin, and gliclazide on the expression and activity of Akt, mTOR, and p70S6K protein kinases in lymphocytes of diabetic patients

The expression of the main effector protein kinase Akt of the PI3K signaling pathway and the activities of mTOR and p70S6K protein kinases in lymphocytes of patients with diabetes mellitus are determined at the combination treatment with insulin and hypoglycemic drugs. It is shown that the Akt exp...

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Veröffentlicht in:Доповіді НАН України
Datum:2018
Hauptverfasser: Sokolova, L.K., Pushkarev, V.M., Belchina, Yu.B., Pushkarev, V.V., Vatseba, T.S., Tronko, M.D.
Format: Artikel
Sprache:English
Veröffentlicht: Видавничий дім "Академперіодика" НАН України 2018
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Online Zugang:https://nasplib.isofts.kiev.ua/handle/123456789/143441
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Effect of combined treatment with insulin, metformin, and gliclazide on the expression and activity of Akt, mTOR, and p70S6K protein kinases in lymphocytes of diabetic patients / L.K. Sokolova, V.M. Pushkarev, Yu.B. Belchina, V.V. Pushkarev, T.S. Vatseba, M.D. Tronko // Доповіді Національної академії наук України. — 2018. — № 8. — С. 105-109. — Бібліогр.: 14 назв. — англ.

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