Effect of combined treatment with insulin, metformin, and gliclazide on the expression and activity of Akt, mTOR, and p70S6K protein kinases in lymphocytes of diabetic patients

• Published in: Доповіді НАН України
• Date: 2018
• Main Authors: Sokolova, L.K., Pushkarev, V.M., Belchina, Yu.B., Pushkarev, V.V., Vatseba, T.S., Tronko, M.D.
• Format: Article
• Language: English
• Published: Видавничий дім "Академперіодика" НАН України 2018
• Subjects: Медицина
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/143441
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Effect of combined treatment with insulin, metformin, and gliclazide on the expression and activity of Akt, mTOR, and p70S6K protein kinases in lymphocytes of diabetic patients / L.K. Sokolova, V.M. Pushkarev, Yu.B. Belchina, V.V. Pushkarev, T.S. Vatseba, M.D. Tronko // Доповіді Національної академії наук України. — 2018. — № 8. — С. 105-109. — Бібліогр.: 14 назв. — англ.

The expression of the main effector protein kinase Akt of the PI3K signaling pathway and the activities of mTOR
 and p70S6K protein kinases in lymphocytes of patients with diabetes mellitus are determined at the combination
 treatment with insulin and hypoglycemic drugs. It is shown...