Studies on interaction of oligoadenylates with proteins in vitro by MALDI-TOF mass spectrometry

• Published in: Вiopolymers and Cell
• Date: 2013
• Main Authors: Levchenko, S.M., Rebriev, A.V., Tkachuk, V.V., Dubey, L.V., Dubey, I.Ya., Tkachuk, Z.Yu.
• Format: Article
• Language: Ukrainian
• Published: Інститут молекулярної біології і генетики НАН України 2013
• Subjects: Structure and Function of Biopolymers
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152396
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Studies on interaction of oligoadenylates with proteins in vitro by MALDI-TOF mass spectrometry / S.M. Levchenko, A.V. Rebriev, V.V. Tkachuk, L.V. Dubey, I.Ya. Dubey, Z.Yu. Tkachuk // Вiopolymers and Cell. — 2013. — Т. 29, №. 1. — С. 42-48. — Бібліогр.: 39 назв. — укр.

Aim. To investigate the ability of «core» 2'-5'- and 3'-5'-oligoadenylates (OA) to interact with α-interferon – a key protein of the 2'- 5'-OAS/RNAase L system responsible for antiviral cell defense. Methods. MALDI-TOF mass spectrometry was used in the studies on protei...