Contribution of chromosomal abnormalities and genes of the major histocompatibility complex to early pregnancy losses

• Date: 2015
• Main Authors: Tkach, I.R., Sosnina, K.O., Huleyuk, N.L., Terpylyak, O.I., Zastavna, D.V., Weise, A., Kosyakova, N., Liehr, T.
• Format: Article
• Language: English
• Published: 2015
• Subjects: Biomedicine
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152432
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Contribution of chromosomal abnormalities and genes of the major histocompatibility complex to early pregnancy losses / I.R. Tkach, K.O. Sosnina, N.L. Huleyuk, O.I. Terpylyak, D.V. Zastavna, A. Weise, N. Kosyakova, T. Liehr // Biopolymers and Cell. — 2015. — Т. 31, № 1. — С. 38-45 . — Бібліогр.: 38 назв. — англ.

Aim. The determination of chromosomal abnormalities in samples from early pregnancy losses and allelic polymorphism of HLA–DRB1 and DQA1 genes in couples with recurrent miscarriage. Methods. Banding cytogenetic and interphase mFISH analysis, DNA extraction by salting method, PCR, agarose gel electro...