Interaction of ubiquitin ligase CBL with LMP2A protein of Epstein-Barr virus occurs via PTB domain of CBL and does not depend on adaptor ITSN1

• Published in: Вiopolymers and Cell
• Date: 2013
• Main Authors: Dergai, O.V., Dergai, M.V., Gudkova, D.O., Tsyba, L.O., Skrypkina, I.Ya., Rynditch, A.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2013
• Subjects: Genomics, Transcriptomics and Proteomics
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152477
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Interaction of ubiquitin ligase CBL with LMP2A protein of Epstein-Barr virus occurs via PTB domain of CBL and does not depend on adaptor ITSN1 / O.V. Dergai, M.V. Dergai, D.O. Gudkova, L.O. Tsyba, I.Ya. Skrypkina, A.V. Rynditch // Вiopolymers and Cell. — 2013. — Т. 29, №. 2. — С. 131-135. — Бібліогр.: 23 назв. — англ.

Aim. Previously Latent membrane protein 2A (LMP2A) of Epstein-Barr virus was found to be ubiquitylated by CBL ubiquitin ligase but no direct interaction of LMP2A with CBL was reported. We aimed to explore this interaction and study a possibility of adaptor protein involvement. Taking into considerat...