Mouse embryonic fibroblasts expressing IFNβ or IL-21 inhibit proliferation of melanoma cells in vitro

• Published in: Вiopolymers and Cell
• Date: 2016
• Main Authors: Vagyna, I.N., Zaharuk, O.A., Strokovska, L.I., Vagyn, Y.V., Kashuba, V.I.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2016
• Subjects: Molecular and Cell Biotechnologies
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152851
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Mouse embryonic fibroblasts expressing IFNβ or IL-21 inhibit proliferation of melanoma cells in vitro / I.N. Vagyna, O.A. Zaharuk, L.I. Strokovska, Y.V. Vagyn, V.I. Kashuba // Вiopolymers and Cell. — 2016. — Т. 32, № 6. — С. 433-441. — Бібліогр.: 37 назв. — англ.

Aim. To study an influence of mouse embryonic fibroblasts (C57Fb) transduced with baculovirus vectors (BVs), encoding genes for murine Ifn-β or human IL21, on survival and proliferation of the malignant mouse melanoma cells (B16) in vitro. Methods. Transduction of cells, construction of BVs, RNA iso...