Hit identification of CK2 inhibitors by virtual screening

• Date: 2017
• Main Authors: Protopopov, M.V., Starosyla, S.A., Borovykov, O.V., Sapelkin, V.N., Bilokin, Y.V., Bdzhola, V.G., Yarmoluk, S.M.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2017
• Series: Вiopolymers and Cell
• Subjects: Bioorganic Chemistry
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152985
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Hit identification of CK2 inhibitors by virtual screening / M.V. Protopopov, S.A. Starosyla, O.V. Borovykov, V.N. Sapelkin, Y.V. Bilokin, V.G. Bdzhola, S.M. Yarmoluk // Вiopolymers and Cell. — 2017. — Т. 33, № 4. — С. 291-301. — Бібліогр.: 30 назв. — англ.

Aim. To search for new CK2 inhibitors by virtual screening. Methods. Virtual screening of a small organic compounds library was performed by molecular docking using the Autodock 4.2.6 package and pharmacophore screening with the “PharmDeveloper” program. The compound activity was determined by in vi...