In vitro and in vivo investigations on anti-influenza effect of adamantyl (alkyl, cycloalkyl) derivatives of aminopropanol-2

• Published in: Вiopolymers and Cell
• Date: 2017
• Main Authors: Voloshchuk, O.M., Korotkiy, Y.V., Rybalko, S.L., Starosila, D.B., Shirobokov, V.P.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2017
• Subjects: Viruses and Cell
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/153122
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: In vitro and in vivo investigations on anti-influenza effect of adamantyl (alkyl, cycloalkyl) derivatives of aminopropanol-2 / O.M. Voloshchuk, Y.V. Korotkiy, S.L. Rybalko, D.B. Starosila, V.P. Shirobokov // Вiopolymers and Cell. — 2017. — Т. 33, № 6. — С. 453-462. — Бібліогр.: 21 назв. — англ.

Aim. To establish anti-influenza activities for 8 compounds of adamantyl (alkyl, cycloalkyl) de-rivatives of aminopropanol-2 in vitro and in vivo investigations. Methods. The antiviral action of compounds was determined in vitro by reduction of infectious titer of the influenza virus in the Madin-Da...