Towards the anti-fibrillogenic activity of phthalocyanines with out-of-plane ligands: correlation with self-association proneness

• Published in: Вiopolymers and Cell
• Date: 2013
• Main Authors: Kovalska, V.B., Losytskyy, M.Yu., Chernii, S.V., Chernii, V.Ya., Tretyakova, I.M., Yarmoluk, S.M., Volkov, S.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2013
• Subjects: Structure and Function of Biopolymers
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/153666
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Towards the anti-fibrillogenic activity of phthalocyanines with out-of-plane ligands: correlation with self-association proneness / V.B. Kovalska, M.Yu. Losytskyy, S.V. Chernii, V.Ya. Chernii, I.M. Tretyakova, S.M. Yarmoluk, S.V. Volkov // Вiopolymers and Cell. — 2013. — Т. 29, №. 6. — С. 473-479. — Бібліогр.: 12 назв. — англ.

Aim. The activity of five hafnium phthalocyanines containing out-of-plane ligands as inhibitors of reaction of insulin fibril formation is studied and correlation between their inhibitory properties and tendency to self-association is discussed. Methods. Fluorescence and absorption spectroscopy. Res...