Synthesis and antitumor activities of new N-(5-benzylthiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides

• Date: 2018
• Main Authors: Ostapiuk, Yu.V., Frolov, D.A., Vasylyschyn, R.Ya., Matiychuk, V.S.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2018
• Series: Вiopolymers and Cell
• Subjects: Bioorganic Chemistry
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/154271
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Synthesis and antitumor activities of new N-(5-benzylthiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides / Yu.V. Ostapiuk, D.A. Frolov, R.Ya. Vasylyschyn, V.S. Matiychuk // Вiopolymers and Cell. — 2018. — Т. 34, № 1. — С. 59-71. — Бібліогр.: 39 назв. — англ.

Aim. Synthesis of series of new N-(5-benzyl-thiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides and study on their anticancer activity. Methods. Organic synthesis, analytical and spectral meth-ods, pharmacological screening. Results. [2-chloro-N-(5-aryl-1,3-thiazol-2-yl)acetamides 3a-h have been prepa...