N-alkylaryl styrylcyanine dyes as fluorescent probes for nucleic acids detection

• Published in: Вiopolymers and Cell
• Date: 2018
• Main Authors: Kuperman, M.V., Snihirova, Y.V., Kryvorotenko, D.V., Losytskyy, M.Yu., Kovalska, V.B., Yarmoluk, S.M.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2018
• Subjects: Bioorganic Chemistry
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/154353
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: N-alkylaryl styrylcyanine dyes as fluorescent probes for nucleic acids detection / M.V. Kuperman, Y.V. Snihirova, D.V. Kryvorotenko, M.Yu. Losytskyy, V.B. Kovalska, S.M. Yarmoluk // Вiopolymers and Cell. — 2018. — Т. 34, № 5. — С. 374-386. — Бібліогр.: 31 назв. — англ.

Aim. To synthesize and characterize a series of N-alkylaryl benzothiazole styrylcyanine dyes as potential fluorescent probes for nucleic acids (NA) detection. Methods. Synthesis, absorption and fluorescence spectroscopy, gel electrophoresis. Results. The modification of N-alkyl styrylcyanine by varia...