Identification of 4‐methoxythieno[2,3‐d]pyrimidines as FGFR1 Inhibitors

Aim. To identify novel FGFR1 inhibitors using virtual screening approach. Methods. We used methods of organic synthesis, molecular docking via the Autodock 4.2.6 program package and in vitro biochemical tests with γ-32P. Results. In vitro experiments showed that 9 of 23 tested compounds possess inhi...

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Published in:Вiopolymers and Cell
Date:2019
Main Authors: Kotey, I.M., Protopopov, M.V., Starosyla, S.A., Balanda, A.O., Pletnova, L.V., Prykhod'ko, A.O., Bdzhola, V.G., Yarmoluk, S.M.
Format: Article
Language:English
Published: Інститут молекулярної біології і генетики НАН України 2019
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Online Access:https://nasplib.isofts.kiev.ua/handle/123456789/154386
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Identification of 4‐methoxythieno[2,3‐d]pyrimidines as FGFR1 Inhibitors / I.M. Kotey, M.V. Protopopov, S.A. Starosyla, A.O. Balanda, L.V. Pletnova, A.O. Prykhod'ko, V.G. Bdzhola, S.M. Yarmoluk // Вiopolymers and Cell. — 2019. — Т. 35, № 2. — С. 152-162. — Бібліогр.: 17 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine