Spectroscopic study of binding of a cationic Pheophorbide-a to an antiparallel quadruplex Tel22

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2019
• Hauptverfasser: Ryazanova, O.A., Zozulya, V.N., Voloshin, I.M., Glamazda, A.Yu., Dubey, I.Ya., Dubey, L.V., Karachevtsev, V.A.
• Format: Artikel
• Sprache: English
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2019
• Schlagworte: Bioorganic Chemistry
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/154389
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Spectroscopic study of binding of a cationic Pheophorbide-a to an antiparallel quadruplex Tel22 / O.A. Ryazanova, V.N. Zozulya, I.M. Voloshin, A.Yu. Glamazda, I.Ya. Dubey, L.V. Dubey, V.A. Karachevtsev // Вiopolymers and Cell. — 2019. — Т. 35, № 2. — С. 129-142. — Бібліогр.: 46 назв. — англ.

Aim. To study the binding of a water-soluble cationic Pheophorbide-a derivative (CatPheo-a) ta a Na+–stabilized antiparallel quadruplex formed by 22-mer oligonucleotide d[AG3(T2AG3)3] of the human DNA telomeric sequence (Tel22, PDB ID: 143D). Methods. Absorption and polarized fluorescence spectrosco...