Evaluation of 4H-4-chromenone derivatives as inhibitors of protein kinase CK2

• Date: 2005
• Main Authors: Prykhodko, A.O., Yakovenko, O.Ya., Golub, A.G., Bdzhola, V.G., Yarmoluk, S.M.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2005
• Series: Біополімери і клітина
• Subjects: Біоорганічна хімія
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/155661
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Evaluation of 4H-4-chromenone derivatives as inhibitors of protein kinase CK2 / A.O. Prykhodko, O.Ya. Yakovenko, A.G. Golub, V.G. Bdzhola, S.M.Yarmoluk // Біополімери і клітина. — 2005. — Т. 21, № 3. — С. 287-292. — Бібліогр.: 43 назв. — англ.

Protein kinase CK2 (Casein Kinase 2) is a ubiquitous serine/threonine protein kinase involved in various cell signal transduction pathways. Thus, CK2 is a new perspective target for anticancer drugs. The receptor-based virtual screening of 2000 compounds from combinatorial library of 4H-4-chromenone...