Interaction of cyanine dyes with nucleic acids. 5. Towards model of «half intercalation» of monomethyne cyanine dyes into double-stranded nucleic acids

• Published in: Биополимеры и клетка
• Date: 1999
• Main Authors: Yarmoluk, S.M., Kovalska, V.B., Kovtun, Y.P.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 1999
• Subjects: Методы
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/156004
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Interaction of cyanine dyes with nucleic acids. 5. Towards model of «half intercalation» of monomethyne cyanine dyes into double-stranded nucleic acids / S.M. Yarmoluk, V.B. Kovalska, Y.P Kovtun // Биополимеры и клетка. — 1999. — Т. 15, № 1. — С. 75-82. — Бібліогр.: 19 назв. — англ.

Recently we have proposed a model of "half intercalation" of monomethyne cyanine dye into the double-stranded helix. Benzothiazole terminal heterocycle «classically» intercalates, nestled between the adjacent base pairs just when second heterocycle is spatially fixed by nucleic acid groove...