Comparison of dual acting drugs and conventional NSAIDs towards parameters of NO-synthase system and oxidative stress in mucosal membrane of large intestine of rats with experimental ulcerative colitis

• Published in: Вiopolymers and Cell
• Date: 2011
• Main Authors: Sklyarov, A.Ya., Lesyk, R.B., Panasyuk, N.B., Fomenko, I.S., Havrylyuk, D.Ya.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2011
• Subjects: Biomedicine
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/156400
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Comparison of dual acting drugs and conventional NSAIDs towards parameters of NO-synthase system and oxidative stress in mucosal membrane of large intestine of rats with experimental ulcerative colitis / SA.Ya. Sklyarov, R.B. Lesyk, N.B. Panasyuk, I.S. Fomenko, D.Ya. Havrylyuk // Вiopolymers and Cell. — 2011. — Т. 27, № 2. — С. 147-153. — Бібліогр.: 24 назв. — англ.

Aim was to compare the action of 2A5DHT compound (dual COX-2/5-LOX inhibitor) and conventional non-steroidal anti-inflammatory drugs towards parameters of nitric oxide (NO) system and intensity of oxidative stress in the mucous membrane of the large intestine (MMLI) in rats with experimental ulcer...