Cerium oxide nanoparticles and metformin increase the reliability of the prooxidant/anti oxidant balance and the survival of ageing rats

• Date: 2020
• Main Authors: Nikitchenko, Yu.V., Klochkov, V.K., Kavok, N.S., Karpenko, N.A., Sedyh, O.O., Nikitchenko, I.V., Bozhkov, A.I., Yefimova, S.L., Seminozhenko, V.P.
• Format: Article
• Language: English
• Published: Видавничий дім "Академперіодика" НАН України 2020
• Series: Доповіді НАН України
• Subjects: Матеріалознавство
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/173762
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Cerium oxide nanoparticles and metformin increase the reliability of the prooxidant/anti oxidant balance and the survival of ageing rats / Yu.V. Nikitchenko, V.K. Klochkov, N.S. Kavok, N.A. Karpenko, O.O. Sedyh, I.V. Nikitchenko, A.I. Bozhkov, S.L. Yefimova, V.P. Seminozhenko // Доповіді Національної академії наук України. — 2020. — № 10. — С. 35-44. — Бібліогр.: 15 назв. — англ.

In comparison with the action of metformin — mimetic of the calorie restricted diet, which prolong the animals lifespan, it has been studied the effect of nanoparticles of cerium dioxide (CeO₂ NPs (1-2 nm)) on survival, physiological indices (the concentration of thyroxine, rectal temperature), as...