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Препаративний метод синтезу 4-(трифлуорометокси)піперидину та 4-(трифлуорометоксиметил)піперидину

Препаративний метод синтезу 4-(трифлуорометокси)піперидину та 4-(трифлуорометоксиметил)піперидину

Aim. To develop a convenient synthetic approach for the preparation of multigram amounts of 4-(trifluoromethoxy)-piperidine and 4-(trifluoromethoxymethyl)piperidine – promising building blocks for medicinal chemistry.Results and discussion. 4-(Trifluoromethoxy)piperidine (8.4 g) and 4-(trifluoromethoxy...

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Bibliographic Details
Main Authors: Logvinenko, Ivan G., Dolovanyuk, Violetta G., Kondratov, Ivan S.
Format: Article
Language:Ukrainian
Published: National University of Pharmacy 2021
Subjects:
флуорування
трифлуорометоксигрупа
ксантат
піперидин
захисна група
fluorination
trifluoromethoxy group
xanthate
piperidine
protection group
Online Access:https://ophcj.nuph.edu.ua/article/view/222669
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https://ophcj.nuph.edu.ua/article/view/222669

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