Синтез функціоналізованих диметилфосфіноїл циклопропанів і циклобутанів

• Date: 2023
• Main Authors: Aleksandrova, Anastasiia M., Cherednichenko, Alona S., Rassukana, Yuliya V.
• Format: Article
• Language: English
• Published: National University of Pharmacy 2023
• Subjects: диметилфосфіноксиди; циклопропан; циклобутан; аміни; карбонові кислоти; dimethylphosphine oxides; cyclopropane; cyclobutane; amines; carboxylic acids
• Online Access: https://ophcj.nuph.edu.ua/article/view/299237
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic procedures for obtaining nitriles, amines and...