Масштабований синтез первинних амінів на основі реакції Петасіса

• Published in: Журнал органічної та фармацевтичної хімії
• Date: 2025
• Volume: 23
• Issue: 1
• Pages: 11-21
• ISSN: 2518-1548
• Author Affiliations: Serhiy V. Ryabukhin — Taras Shevchenko National University of Kyiv; Institute of Organic Chemistry of the National Academy of Sciences of Ukraine; Enamine Ltd; Maksym V. Herasymchuk — Taras Shevchenko National University of Kyiv; Enamine Ltd
• Main Authors: Ryabukhin, Serhiy V., Herasymchuk, Maksym V.
• Format: Article
• Language: English
• Published: National University of Pharmacy 2025
• Subjects: реакція Петасіса; трикомпонентна реакція; первинні аміни; багатограмовий синтез
• Online Access: https://ophcj.nuph.edu.ua/article/view/324183
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

The efficient and scalable synthesis of homoallylic amines is a subject of significant interest due to the potential applications of these compounds in medicinal and synthetic chemistry. The three-component Petasis reaction is an excellent approach for obtaining these compounds. Based on previous st...