Ефективний метод синтезу бензоконденсованих п’ятичленних циклічних сульфаматів

• Date: 2026
• Main Authors: Aleksandrenko, Serhii H., Vashchenko, Bohdan V.
• Format: Article
• Language: English
• Published: National University of Pharmacy 2026
• Subjects: гетероцикли; сульфурорганічні сполуки; сульфамати
• Online Access: https://ophcj.nuph.edu.ua/article/view/358460
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

An efficient and scalable method for the synthesis of 1,2,3-benzoxathiazole 2,2-dioxides and related five-membered cyclic sulfamates employing gaseous sulfuryl fluoride (SO2F2) in the presence of Et3N is described. The one-pot cyclization of 2-aminophenol derivatives proceeds at rt and tolerates a v...