Синтез і протипухлинна активність 2-(4-aміно-5-метил-4H-[1,2,4]триазол-3-ілсульфаніл)-N-(5-R-бензилтіазол-2-іл)-ацетамідів
3-Aryl-2-chloropropanals 2a-h have been prepared by the reaction of arenediazonium chlorides 1a-h with acrolein in the conditions of Meerwein arylation (water-acetone, CuCl2 as a catalyst). These aldehydes react with thiourea by refluxing in ethanol to obtain 2-amino-5-R-benzyl-1,3-thiazoles 3a-h (R...
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| Date: | 2015 |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
National University of Pharmacy
2015
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| Subjects: | |
| Online Access: | https://ophcj.nuph.edu.ua/article/view/ophcj.15.865 |
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| Journal Title: | Journal of Organic and Pharmaceutical Chemistry |