Обоснование возможности использования эмбриональных нервных клеток при лечении органоспецифических аутоиммунных заболеваний

Обоснование возможности использования эмбриональных нервных клеток при лечении органоспецифических аутоиммунных заболеваний

There was studied the possibility of this pathology treatment with intraperitoneal introduction of native and cryopreserved embryonic neuronal cells (ENCs) in the model of allergic encephalomyelitis as experimental analogue of multiple sclerosis (MS). The efficiency of performed therapy is establish...

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Bibliographic Details
Date:2006
Main Authors: Goltsev, A. N., Babenko, N. N.
Format: Article
Language:English
Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2006
Subjects:
трансплантація ембріональних нервових клітин
кріоконсервування
алергічний енцефаломієліт
Online Access:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1030
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Journal Title:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
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Summary:There was studied the possibility of this pathology treatment with intraperitoneal introduction of native and cryopreserved embryonic neuronal cells (ENCs) in the model of allergic encephalomyelitis as experimental analogue of multiple sclerosis (MS). The efficiency of performed therapy is established to be determined both by morphofunctional status of transplants and their introduction terms, i.e. to the 7th and 14th day of the pathological process development. It has been noted that cryopreserved ENCs (cENCs) in contrast to native ENCs (nENCs) during the introduction had correction peculiarities of clinical and neurological status of animals, immune regulatory index, killer activity of splenocytes and content of finely dispersed circulating immune complexes (fCIC) in blood serum.

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