Влияние инкубации с криопротекторами на количество эпитопов Gal-α-1,3-Gal в клетках линии PK-15

• Date: 2016
• Main Authors: Bohuslavskyi, Konstantin I., Alabedalkarim, Natalia M., Pakhomov, Alexsandr V., Bozhok, Galyna A.
• Format: Article
• Language: English
• Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2016
• Subjects: епітоп Gal-α-1; 3-Gal; кріопротектори; диметилсульфоксид; поліетиленгліколь
• Online Access: https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1242
• Journal Title: Problems of Cryobiology and Cryomedicine

Transplantation of bioprostheses derived from bovine and porcine tissues is an advanced method of correcting defects in blood vessels and valves, however when using it a hyperacute immune response associated with the presence of Gal-alpha- 1,3-Gal (α-Gal epitope) on the surface of cell membranes ca...