Влияние инкубации эритроцитов лошади при 49°С на эффективность амфифильных веществ в условиях гипертонического стресса

Влияние инкубации эритроцитов лошади при 49°С на эффективность амфифильных веществ в условиях гипертонического стресса

The effect of amphiphilic compounds (C10, DM, TFP) and heat preliminary treatment of equine erythrocytes (49°C) on cell sensitivity to hypertonic stress (4.0 M NaCl) has been investigated. All amphiphilic compounds were shown as reducing the level of hypertonic hemolysis in equine erythrocytes. Ery...

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Bibliographic Details
Date:2009
Main Authors: Shpakova, N. M., Pisarenko, N. A., Orlova, N. V.
Format: Article
Language:English
Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2009
Subjects:
еритроцити коня
гіпертонічний гемоліз
спектрин
амфіфільні сполуки
Online Access:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/286
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Journal Title:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
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Summary:The effect of amphiphilic compounds (C10, DM, TFP) and heat preliminary treatment of equine erythrocytes (49°C) on cell sensitivity to hypertonic stress (4.0 M NaCl) has been investigated. All amphiphilic compounds were shown as reducing the level of hypertonic hemolysis in equine erythrocytes. Erythrocyte incubation at 49°C, resulting in spectrin denaturation, reduces the level of erythrocyte hypertonic damage at 37°C and increases it at 0°C. A decrease in the efficiency of all studied amphiphilic compounds is observed under the mentioned conditions.

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