Синтез та властивості нанокомпозитів Fe3O4/гідроксіапатит/памідронова кислота/ діетилентриамінпентаоцтова кислота/Gd3+

The novel Gd- containing magnetically sensitive nanocomposites were synthesized using the single-domain magnetite (Fe3O4), hydroxyapatite (HA), pamidronic acid (PA), diethylenetriaminepentaacetic acid (DTPA), gadolinium. We attached constituents sequentially to the surface of the compound that was s...

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Datum:2017
Hauptverfasser: Pylypchuk, Ie. V., Zubchuk, Yu. O., Petranovskaya, A. L., Turanska, S. P., Gorbyk, P. P.
Format: Artikel
Sprache:Ukrainisch
Veröffentlicht: Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine 2017
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Online Zugang:https://www.cpts.com.ua/index.php/cpts/article/view/338
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Назва журналу:Chemistry, Physics and Technology of Surface

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Chemistry, Physics and Technology of Surface
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Zusammenfassung:The novel Gd- containing magnetically sensitive nanocomposites were synthesized using the single-domain magnetite (Fe3O4), hydroxyapatite (HA), pamidronic acid (PA), diethylenetriaminepentaacetic acid (DTPA), gadolinium. We attached constituents sequentially to the surface of the compound that was synthesized in the previous reaction. Finally we synthesized nanocomposite Fe3O4/hydroxyapatite (HA)/ pamidronic acid (PA)/diethylenetriaminepentaacetic acid (DTPA)/gadolinium (Gd). Сomposition and structure of the nanocomposites were studied by FTIR spectroscopy, XRD and NMR. The synthesized nanocomposites can be used in medicine and biology, particularly in neutron capture therapy. They can serve as a multifunctional radio therapeutic drugs and diagnostic tools for targeted delivery, accumulation and retention of an external magnetic field.