Магнітні рідини на основі магнетиту і доксорубіцину для спрямованої доставки лікарського засобу

Technological methods for synthesis of new magnetic liquids based on modified magnetite colloidal systems containing chemotherapeutic agent doxorubicin are developed. The magnetite surface modifying was carried out with hydroxyapatite, the magnetic liquid was stabilized with sodium oleate and polyet...

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Datum:2017
Hauptverfasser: Petranovska, A. L., Abramov, N. V., Turanska, S. P., Gorbyk, P. P., Kusyak, A. P.
Format: Artikel
Sprache:Ukrainisch
Veröffentlicht: Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine 2017
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Online Zugang:https://www.cpts.com.ua/index.php/cpts/article/view/340
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Назва журналу:Chemistry, Physics and Technology of Surface

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Chemistry, Physics and Technology of Surface
Beschreibung
Zusammenfassung:Technological methods for synthesis of new magnetic liquids based on modified magnetite colloidal systems containing chemotherapeutic agent doxorubicin are developed. The magnetite surface modifying was carried out with hydroxyapatite, the magnetic liquid was stabilized with sodium oleate and polyethylene glycol to give biocompatible properties and low ability to adsorb plasma proteins. Physico-chemical properties of developed colloid systems have been studied.