Сравнительная характеристика частоты сердечных сокращений у крыс при различных методах холодовых воздействий

Comparative characteristics of cardiac rate in rats of different age groups, cooled by both methods of standard extreme cryotherapy and rhythmic one, proposed by the author, have been presented. Negative chronotropic effect after norepinephrine intraperitoneal introduction into rats is observed only...

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Bibliographic Details
Date:2007
Main Author: Babijchuk, V. G.
Format: Article
Language:English
Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2007
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Online Access:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/493
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Journal Title:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
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Summary:Comparative characteristics of cardiac rate in rats of different age groups, cooled by both methods of standard extreme cryotherapy and rhythmic one, proposed by the author, have been presented. Negative chronotropic effect after norepinephrine intraperitoneal introduction into rats is observed only after the 9th cooling session by the standard method and after the 3rd one if cooling with the rhythmic effects, that might testify to earlier terms of blood brain barrier (BBB) permeability for neuromediator. This may be confirmed by pinocytosis activation in capillary endotheliocytes, as well as by revealing the horse radish peroxidase granules in endotheliocyte fragments of cerebral capillary.